For most travellers to Greenland flying is the only option. Air Greenland flies from Denmark to Kangerlussuaq most weekdays in summer (less often in winter) and to Narsarsuaq 1-3 times a week depending on season. The company can then connect you throughout Greenland with their commuter flights in either Dash-7 aircraft or Bell Helicopter. The flight to Greenland from Europe would be in a 757 or A330 aircraft. It is important to realise that weather conditions can be extreme with delayed and cancelled flights as a consequence.

It is also possible to fly from Reykjavík to Nuuk by Air Greenland and Air Iceland (which is different from Icelandair). There are no regular connections from North America.